Class A requires evidence from at least one high quality/well conducted meta-analysis, systematic review, or randomised controlled trial with a very low/low risk of bias that is directly applicable to the target population and demonstrates overall consistency of results

Class A requires evidence from at least one high quality/well conducted meta-analysis, systematic review, or randomised controlled trial with a very low/low risk of bias that is directly applicable to the target population and demonstrates overall consistency of results

epic2	For the full guidelines, visit: www.epic.tvu.ac.uk
Funded and endorsed by the Department of Health, the new epic2 guidelines have been developed by a nurse-led, multi-professional team of researchers and specialist clinicians.
CVAD15 Decontaminate the skin site with a single patient use application of alcoholic chlorhexidine gluconate solution (preferably 2% chlorhexidine gluconate in 70% isopropyl alcohol) prior to the insertion of a central venous access device [2] [Class A]
CVAD 24 An alcoholic chlorhexidine gluconate solution (preferably 2% chlorhexidine gluconate in 70% isopropyl alcohol) should be used to clean the catheter insertion site during dressing changes, and allowed to air dry. An aqueous solution of chlorhexidine gluconate should be used if the manufacturer's recommendations prohibit the use of alcohol with their products [2] [Class A]
"Skin cleansing/antisepsis of the insertion site is regarded as one of the most important measures for preventing catheter-related infection” [2]